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Breakage

Tablet Core

  • Tablets are too soft or too brittle Investigate core improvement
  • Tablets cap/laminate Change tablet compression profile
  • Poor tablet shape for coating Change tablet shape

Process/Equipment

  • Pan speed too high Decrease pan speed
  • Inappropriate baffle design for tablet shape Change baffle design
  • Spray rate too low Increase spray rate
  • Suspension solids concentration too low Increase suspension solids concentration (if possible)

Further Resources