Opadry® Complete Film Coating System


Opadry is Colorcon’s original, customized, one-step film coating system which combines polymer, plasticizer and pigment, as required, in a dry concentrate. Use of an Opadry film coating will result in attractive, elegant coatings on a variety of tablet cores. Opadry systems can be easily dispersed in aqueous or organic solvent solutions.
Product Literature
Product Application Data General Information Product Process Parameters Product Recon Sheet Published Posters Published White Papers / ArticlesProduct Application Data

Modern Tablet Film Coatings and Influence on Ease of Swallowing
View and DownloadThis Application Data Sheet is extracted from a study of esophageal transit times using uncoated and film-coated caplets,oval tablets, plus hard and soft-gelatin capsules. Reprint of poster presented at the American Association of Pharmaceutical Scientists Meeting, 2003.
Technical Bulletin:Film Coating of Hydrophilic Matrices
View and DownloadFilm Coating of Hydrophilic Matrix Tablets : Safety Considerations for Product Design to Minimize Medication Errors
General Information

Opadry® Cleaning Instructions
View and DownloadGeneral directions for clean up after use of most Opadry product formulations.
Tech Bulletin: Introducing Surelease® | Opadry® for Taste-Masking
View and DownloadIntroduction to Taste-Masking with Surelease and Opadry
Tech Bulletin: Surelease® | Opadry® for Taste-Masking 2
View and DownloadTaste-masking with Surelease® and Opadry: Impact of Substrate Morphology
Product Process Parameters

Opadry® Coating Parameters
View and DownloadStarting process recommendations for use of Opadry aqueous formulations.
Opadry® Coating Parameters - Organic Formulations
View and DownloadStarting process recommendations for use of Opadry formulations using an isopropyl alcohol/methylene chloride solvent solution.
Product Recon Sheet

Opadry® Reconstitution Procedures
View and DownloadMixing procedure and holding instructions for Opadry coating formulations.
Published Posters

AAPS 2012 - Barrier Membrane Coated Hydrophilic Matrices: Robustness of Metoprolol Tartrate Release under Biorelevant Test Conditions – Impact of Media Composition
View and DownloadJoint poster - Ernst Moritz Arndt University & Colorcon
AAPS 2019 - Novel Authentication Technology Using Molecular Tags as a PCID in Solid Oral Dosage Forms
View and DownloadPoster Reprint from AAPS 2019 in San Antonio, TX, US.
AAPS 2020 - Evaluation of Different Opadry® Film Coating Systems on Tablets Containing Amorphous Solid Dispersion of Itraconazole
View and DownloadAAPS 2020 - Evaluation of Various Formulations and Processes on Barrier Membrane Coating of a BCS Class 1 Drug with Aquacoat® ECD-30
View and DownloadAAPS 2020 - In Vitro Evaluation of an Enteric Coating System for Esomeprazole Delayed Release Multiparticulates for Administration Through Nasogastric Tube
View and DownloadAAPS 2021 - Drug Release Stability of Propranolol Hydrochloride ER Multiparticulates using Ethylcellulose Dispersions
View and DownloadAAPS 2021 - Evaluation of Enteric Coating of Mini-Tabs in Different pH Media Using Acryl-EZE® II System
View and DownloadAAPS 2021 - Impact of Opacifier Type in a Film Coating Formulation on Photostability of Tablet Ingredients
View and DownloadAAPS 2021 - Investigation of a Directly Compressible Pantoprazole Sodium Delayed Release Formulation
View and DownloadAAPS 2021 - Performance and Stability of an On-Dosage Authentication Technology Using Molecular Tags on the Coated a Model Active
View and DownloadCRS 2012 - Barrier Membrane Coating of Hydrophilic Matrices of a Very Soluble Drug, Metoprolol Tartrate at High Dose: A Strategy to Eliminate the Initial Burst Release
View and DownloadApplication of barrier membrane (BM) coating, using Surelease with a pore-former, Opadry; elimination of the burst effect, followed by near zero order release.
CRS 2013 - Barrier Membrane Coating of Hydrophilic Matrices: A Simplified Strategy to Attain Zero Order Drug Release
View and DownloadAlternative formulation strategy for dosage forms where zero order release of drug is desired
CRS 2018 - Simultaneous Application of a Two-part Delayed Release Coating in a Single Pass Continuous Coating Process
View and DownloadPublished White Papers / Articles

CRS 2021 - Evaluation of Formulated Ethylcellulose Aqueous Dispersions to Develop Controlled Release Multiparticulate Formulation of Freely Soluble Drug, Propranolol Hydrochloride
View and DownloadDare to be Different - Use Color and Shape for Unique Tablet Design
View and DownloadThis article is from Medicine Maker, March 2015 issue.
Film Coating for Pediatric Oral Solid Dosage Forms
View and DownloadGetting the Right Coating for Pediatric Tablet Formulations
Film Coating for Taste-masking of Pediatric Oral Solid Dosage Forms
View and DownloadCase study on the use of Surelease® and Opadry® in the Development of a Paediatric Form of Raltegravir
From Core to Coating - A Supplement from The Medicine Maker
View and DownloadA series of articles published in The Medicine Maker collated into a Supplement “From Core to Coating”
• Speed and Simplicity – A Formulator’s Best Friend in Development
• The Power of Productivity
• Staying On Trend
Implementing On-Dose Authentication Technologies for Solid Dose Drug Products
View and DownloadIn this whitepaper, we look at robust strategies that manufacturers can adopt to protect their supply chain from external threats.
Manufacturing Pressure Accelerates Move to Fully Formulated Film Coatings
View and DownloadArticle published in The Manufacturing Chemist / Nutraceutical Business Review - September 2020
On Drug Delivery
View and DownloadTaste-masking interview from On Drug Delivery July 2015 edition. Taste-masking and the positive impact on medication adherence. Review of pH dependent and independent film coating options.
The Trusted Tablet
View and DownloadMass digitalization of medicines offers new levels of
supply chain security and transparency
Key benefits include:
- Elimination of separate inventories of polymer, plasticizer and pigment
- Batch-to-batch color consistency
- On-time delivery through manufacturing plants in key pharmaceutical markets worldwide
Opadry provides excellent film forming capabilities and benefits include:
- High opacity and tensile strength
- Sharp logo definition
- Good adhesion
Recommended Use:
- Can be utilized in both aqueous and organic (hydro-alcoholic) coating procedures