Opadry® Complete Film Coating System
Opadry is Colorcon’s original, customized, one-step film coating system which combines polymer, plasticizer and pigment, as required, in a dry concentrate. Use of an Opadry film coating will result in attractive, elegant coatings on a variety of tablet cores. Opadry systems can be easily dispersed in aqueous or organic solvent solutions.
Product LiteratureProduct Application Data General Information Product Process Parameters Product Recon Sheet Published Posters Published White Papers / Articles
Product Application Data
Modern Tablet Film Coatings and Influence on Ease of SwallowingView and Download Send by Email
This Application Data Sheet is extracted from a study of esophageal transit times using uncoated and film-coated caplets,oval tablets, plus hard and soft-gelatin capsules. Reprint of poster presented at the American Association of Pharmaceutical Scientists Meeting, 2003.
Technical Bulletin:Film Coating of Hydrophilic MatricesView and Download Send by Email
Film Coating of Hydrophilic Matrix Tablets : Safety Considerations for Product Design to Minimize Medication Errors
Opadry® Cleaning InstructionsView and Download Send by Email
General directions for clean up after use of most Opadry product formulations.
Tech Bulletin: Introducing Surelease® | Opadry® for Taste-MaskingView and Download Send by Email
Introduction to Taste-Masking with Surelease and Opadry
Tech Bulletin: Surelease® | Opadry® for Taste-Masking 2View and Download Send by Email
Taste-masking with Surelease® and Opadry: Impact of Substrate Morphology
Product Process Parameters
Opadry® Coating ParametersView and Download Send by Email
Starting process recommendations for use of Opadry aqueous formulations.
Opadry® Coating Parameters - Organic FormulationsView and Download Send by Email
Starting process recommendations for use of Opadry formulations using an isopropyl alcohol/methylene chloride solvent solution.
Product Recon Sheet
Opadry® Reconstitution ProceduresView and Download Send by Email
Mixing procedure and holding instructions for Opadry coating formulations.
AAPS 2012 - Barrier Membrane Coated Hydrophilic Matrices: Robustness of Metoprolol Tartrate Release under Biorelevant Test Conditions – Impact of Media CompositionView and Download Send by Email
Joint poster - Ernst Moritz Arndt University & Colorcon
AAPS 2019 - Novel Authentication Technology Using Molecular Tags as a PCID in Solid Oral Dosage FormsView and Download Send by Email
Poster Reprint from AAPS 2019 in San Antonio, TX, US.
AAPS 2020 - Evaluation of Different Opadry® Film Coating Systems on Tablets Containing Amorphous Solid Dispersion of ItraconazoleView and Download Send by Email
AAPS 2020 - Evaluation of Various Formulations and Processes on Barrier Membrane Coating of a BCS Class 1 Drug with Aquacoat® ECD-30View and Download Send by Email
AAPS 2020 - In Vitro Evaluation of an Enteric Coating System for Esomeprazole Delayed Release Multiparticulates for Administration Through Nasogastric TubeView and Download Send by Email
AAPS 2021 - Drug Release Stability of Propranolol Hydrochloride ER Multiparticulates using Ethylcellulose DispersionsView and Download Send by Email
AAPS 2021 - Evaluation of Enteric Coating of Mini-Tabs in Different pH Media Using Acryl-EZE® II SystemView and Download Send by Email
AAPS 2021 - Impact of Opacifier Type in a Film Coating Formulation on Photostability of Tablet IngredientsView and Download Send by Email
AAPS 2021 - Investigation of a Directly Compressible Pantoprazole Sodium Delayed Release FormulationView and Download Send by Email
AAPS 2021 - Performance and Stability of an On-Dosage Authentication Technology Using Molecular Tags on the Coated a Model ActiveView and Download Send by Email
AAPS 2022 - Application of Film Coating Systems to Hide Dark Spots on Multivitamin TabletsView and Download Send by Email
AAPS Poster Reprint 2022
AAPS 2022- Impact of Coating Process Parameters on Drug Layering of Sitagliptin Over Metformin HCl ER TabletsView and Download Send by Email
AAPS Poster Reprint 2022
CRS 2012 - Barrier Membrane Coating of Hydrophilic Matrices of a Very Soluble Drug, Metoprolol Tartrate at High Dose: A Strategy to Eliminate the Initial Burst ReleaseView and Download Send by Email
Application of barrier membrane (BM) coating, using Surelease with a pore-former, Opadry; elimination of the burst effect, followed by near zero order release.
CRS 2013 - Barrier Membrane Coating of Hydrophilic Matrices: A Simplified Strategy to Attain Zero Order Drug ReleaseView and Download Send by Email
Alternative formulation strategy for dosage forms where zero order release of drug is desired
CRS 2018 - Simultaneous Application of a Two-part Delayed Release Coating in a Single Pass Continuous Coating ProcessView and Download Send by Email
CRS 2021 - Evaluation of Formulated Ethylcellulose Aqueous Dispersions to Develop Controlled Release Multiparticulate Formulation of Freely Soluble Drug, Propranolol HydrochlorideView and Download Send by Email
Published White Papers / Articles
Dare to be Different - Use Color and Shape for Unique Tablet DesignView and Download Send by Email
This article is from Medicine Maker, March 2015 issue.
Film Coating for Pediatric Oral Solid Dosage FormsView and Download Send by Email
Getting the Right Coating for Pediatric Tablet Formulations
Film Coating for Taste-masking of Pediatric Oral Solid Dosage FormsView and Download Send by Email
Case study on the use of Surelease® and Opadry® in the Development of a Paediatric Form of Raltegravir
From Core to Coating - A Supplement from The Medicine MakerView and Download Send by Email
A series of articles published in The Medicine Maker collated into a Supplement “From Core to Coating”
• Speed and Simplicity – A Formulator’s Best Friend in Development
• The Power of Productivity
• Staying On Trend
Implementing On-Dose Authentication Technologies for Solid Dose Drug ProductsView and Download Send by Email
In this whitepaper, we look at robust strategies that manufacturers can adopt to protect their supply chain from external threats.
Manufacturing Pressure Accelerates Move to Fully Formulated Film CoatingsView and Download Send by Email
Article published in The Manufacturing Chemist / Nutraceutical Business Review - September 2020
On Drug DeliveryView and Download Send by Email
Taste-masking interview from On Drug Delivery July 2015 edition. Taste-masking and the positive impact on medication adherence. Review of pH dependent and independent film coating options.
The Trusted TabletView and Download Send by Email
Mass digitalization of medicines offers new levels of
supply chain security and transparency
Key benefits include:
- Elimination of separate inventories of polymer, plasticizer and pigment
- Batch-to-batch color consistency
- On-time delivery through manufacturing plants in key pharmaceutical markets worldwide
Opadry provides excellent film forming capabilities and benefits include:
- High opacity and tensile strength
- Sharp logo definition
- Good adhesion
- Can be utilized in both aqueous and organic (hydro-alcoholic) coating procedures
Colorcon can help to reduce your project time by providing the right solution through excipient selection and process guidance.
Lower total cost and reduce time to market
Life cycle management through modified delivery profiles and product line extensions
Reduce medication errors and improve patient adherence
Stable and consistent product performance
Track and trace