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Tablet-To-Tablet Color Variation

Tablet Core

  • Poor tablet shape Optimize tablet shape for mixing

Coating Formulation

  • Suspension solids concentration too high Decrease suspension solids concentration (if possible)
  • Low opacity of film coating Select a high opacity film coating from Colorcon

Process/Equipment

  • Low film coat weight gain Increase weight gain of film coating
  • Pan speed too low Increase pan speed
  • Insufficient number of spray guns Increase number of spray guns
  • Pan load too low Increase pan load
  • Poor baffle design Improve baffle design
  • Poor spray gun design or setup Correct gun setup: gun design, gun spacing, gun-to-bed distance, fan width, suspension flow rate balance, or use a better spray gun

Further Resources