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Film Cracking

Tablet Core

  • Core and coating have different thermal expansion properties Reduce mineral type fillers in the core formulation, eg. calcium carbonate, calcium sulfate, magnesium carbonate
  • Lack of relaxation time between tablet compression and coating Extend time between tableting and coating

Coating Formulation

  • Poorly plasticized film coating Select an optimally plasticized film coating from Colorcon

Process/Equipment

  • Expansion of core due to heating Avoid high tablet bed temperatures

Further Resources