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Color Variation

Tablet Core

  • Core ingredients (usually moisture sensitive) migrate (bleed) through the coating Use an isolating seal-coat

Coating Formulation

  • Pigments are poorly dispersed Select a fully formulated film coating from Colorcon
  • Core ingredients interact with film coating to cause color instability Select a different film coating from Colorcon
  • Liquid plasticizer migration Select a film coating with a solid plasticizer from Colorcon
  • Low opacity film coating Select a high opacity film coating from Colorcon

Process/Equipment

  • Core overwet during coating Increase tablet bed temperature

Further Resources