METHOCEL™ Premium DC2 Cellulose Ethers
Available as directly compressible grades, METHOCEL™ DC2 polymers deliver exceptional flow properties and process capability as well as consistent modified release performance for matrix formulations. METHOCEL™ DC2 enable manufacturers to replace costly wet granulation in matrix tablet production with cost effective dry granulation and direct compression techniques.
METHOCEL™ DC2 helps you enjoy the benefits of dry powder processing techniques:
- improved powder flow
- lower manufacturing costs by up to 60%
- shorten development time
- results in more reproducible and robust tablet properties
- better formulation option for heat and moisture-sensitive APIs
- no additives, means no regulatory hurdles, as METHOCEL™ DC2 is pure HPMC
Two direct compression grades of METHOCEL™ DC2 are available: K100 LV, and K100M; chemically identical to current METHOCEL™ Premium products and meet USP, PhEur and JP specifications.
Colorcon, through the Controlled Release Alliance, has exclusive, global sales and distribution rights for METHOCEL™ products from IFF for use in controlled release applications.METHOCEL™ is a trademark of International Flavors and Fragrances Inc. or its affiliates. © 2021 IFF. All rights reserved
Product LiteratureProduct Application Data General Information Product Brochure Published Posters Published White Papers / Articles
Product Application Data
METHOCEL™ DC2 Product Information BrochureView and Download Send by Email
METHOCEL DC2 Premium Excipients help you enjoy the benefits of dry powder processing techniques
while maintaining consistent modified release performance. They offer the performance and reliability expected from the proven family of METHOCEL™ excipients.
CRS 2012 - Barrier Membrane Coating of Hydrophilic Matrices of a Very Soluble Drug, Metoprolol Tartrate at High Dose: A Strategy to Eliminate the Initial Burst ReleaseView and Download Send by Email
Application of barrier membrane (BM) coating, using Surelease with a pore-former, Opadry; elimination of the burst effect, followed by near zero order release.
Published White Papers / Articles
Streamline Manufacture of Modified Release Matrix Tablets via Direct CompressionView and Download Send by Email
In this whitepaper, we describe how to get to market faster with directly compressible hypromellose (HPMC), which bypasses time-consuming and labor-intensive wet granulation, saves processing time and cost, and lowers regulatory hurdles due to reduced manufacturing steps and complexity.
Colorcon can help to reduce your project time by providing the right solution through excipient selection and process guidance.
Lower total cost and reduce time to market
Life cycle management through modified delivery profiles and product line extensions
Reduce medication errors and improve patient adherence
Stable and consistent product performance
Track and trace