The Solid Dose

Edition 3, 2021


Formulating Veterinary Medicines 

For veterinary medicinal products (VMP), compliance and convenience are critical to ensure the success of prevention, control and treatment. There is a recognized need for highly palatable solid oral dosage forms, especially for companion animals that prefer pleasant-tasting medications and should be provided with safe and dependable VMPs. To improve the uptake of VMP and supplements Colorcon provides formulation insights to promote palatability and voluntary acceptance.

With chewable dosage forms for companion pets becoming more prevalent, Starch 1500®, partially pregelatinized maize starch, is proving to be a key excipient in VMP formulation. Benefits of using Starch 1500® in veterinary dosage forms include: 

  • Neutral taste with good palatability 
  • Good thermal stability, ideal for VMP soft chew manufacture  
  • Imparts plasticity (ductility) to the dosage form and helps maintain these properties over the shelf-life of the product
  • No animal products/ by-products used in manufacturing Starch 1500 
  • Reduced process and material costs by eliminating binders/ super-disintegrants/ high levels of lubricants & glidants 

Colorcon has extended its flagship capabilities to animal health products, enabling formulation development from the basic core materials to the final dosage form. Whether developing a chewable or a tablet, our materials provide improved stability and taste-masking for animal pharmaceutical and supplement products. 

Colorcon is proud to announce it has recently qualified as a Preferred Supplier with the National Animal Supplement Council (NASC). 

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TiO2 Free Coating

As of May 2021, the European Food Safety Authority (EFSA) announced titanium dioxide (TiO2) is no longer acceptable for use as a food additive (E 171). Colorcon has been prepared for this decision for some time and can provide Nutrafinish® TiO2 Free Coatings that afford good opacity with aesthetic appeal, while addressing this concern. 

Colorcon's Nutrafinish, TiO2 Free Coatings:
  • Ensure a superior tablet finish appealing to consumers 
  • Provide efficient and reproducible manufacturing performance 
  • Available using non-synthetic (natural) colorants 
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Why Film Coat?

With over 1.4 trillion tablets produced per year (IQVIA Midas Report), every second of the day, someone is consuming a tablet (pill).

As the pharmaceutical industry evolves, Colorcon continues to lead with advances in film coating technology by the application of a thin, even, and continuous film around the surface of a tablet, creating an elegant finish, protecting, and allowing for branding and trademark opportunities. Film coating makes medicines easier to swallow, simpler to identify, enhances in-use stability, and masks unpleasant tastes.

Check out our latest video showing how easy the application of a film coating can be. 

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Online Problem Solving

Colorcon’s experienced technical service team helps customers with problem solving, from product concept design to the final production, reducing development time.

The Troubleshooting Guide is just one of the useful tools developed to help our customers quickly identify and resolve issues.  

The Guide provides insight into increasing manufacturing efficiency while improving product quality. Visit our website to find solutions to commonly seen process issues that can result in tablet breakage, logo bridging, edge erosion and coating issues.

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Best Abstract Award
AAPS PharmSci 360 2021 
Daniel To, Manager – Product Development at Colorcon, has been selected as a recipient of the American Association of Pharmaceutical Scientists (AAPS) 2021 Best Abstract Award.

His abstract, “Performance and Stability of an On-Dosage Authentication Technology Using Molecular Tags on the Coated a Model Active,” was among the top 10% of submitted abstracts.

His poster, as well as several others, will be presented during the AAPS 2021 PharmSci 360 hybrid meeting, October 17-20 in Philadelphia, PA, USA.

In case you missed last year's, you can still access 2020 AAPS posters here. 

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Published Posters Controlled Release Society 2021 

In July, Colorcon’s development scientists attended the Controlled Release Society (CRS) 2021 virtual event, presenting posters on three innovative scientific topics, featuring barrier membrane coating with Aquacoat® ECD-30, Surelease®, and drug-resin complexation. The posters can be accessed through the links provided: Read more

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