Hydrophilic Matrix Tablets
Hydrophilic matrix tablets are utilized in greater than 75% of the controlled release products on the market today and are applicable across a broad range of therapeutic categories. Matrix systems are popular because they are well understood and can be manufactured with conventional equipment and processes, and have broad regulatory acceptance. In addition, consistent control of drug release has been successfully demonstrated in marketed products containing high and low drug dose. Due to the array of polymers available for use in hydrophilic matrix tablets, drug release can be fine tuned for drugs of low, medium, or high solubility.
Colorcon's HyperStart®, oral solid dose starting formulation service, can assist you in selecting the right polymer and suggested starting formulation for your desired release profile.