Surelease® Ethylcellulose Dispersion Type B NF

Surelease is a complete, sustained release, aqueous coating system utilizing ethylcellulose as the rate controlling polymer for drug release. The dispersions are a unique combination of film-forming polymer, plasticizer and stabilizers; that can be used for sustained release coating and taste masking applications. This established technology provides reliable and reproducible release profiles that are consistent from the laboratory, to pilot and production scale processes.

  • Drug release is primarily by diffusion through the Surelease semipermeable membrane
  • Rate of drug release is modified by increasing or decreasing the amount of Surelease applied (film thickness)
  • Uniform drug release independent of pH
  • Taste masking application

The easy adjustment of release profiles provides significant time savings both in development and production. Furthermore, process optimization ensures the coating is fully coalesced, which may eliminate the need for a curing step. Surelease is also safe to use with components that meet the requirements of major pharmacopeia, and registered product approvals worldwide.

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