Functional Excipients for the Formulation of Solid Oral Dosage Forms
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Application of Opadry® II, complete film coating system, on metformin HCl extended release matrices containing POLYOX™ water soluble resinApplication Data on Polyox
Dissolution Testing for POLYOX™ Extended Release MatricesApplication Data on Polyox
Evaluation of Various Materials for Cleaning of Processing Area and Equipment After Using POLYOX™ PolymersApplication Data for Polyox
Formulation of POLYOX™ ER Matrices for a Highly Soluble ActiveApplication Data
Physico-mechanical Characterization of POLYOX™ for Tablet ManufactureApplication Data on Polyox
The Influence of In Vitro Dissolution Method on the Release of a Highly Water Soluble Drug from Polyethylene Oxide and Hypromellose Hydrophilic Extended Release MatricesThis ADS was adapted from the 2008 AAPS poster. The objective of this study was to investigate the influence of different dissolution methods on the release of a high solubility drug from an ER matrix formulation containing either HPMC or PEO as the rate-controlling polymer.
POLYOX™ Product Information BrochureIntroduction to the POLYOX™ line of water soluble resins.
Effect of Filler Type on the Stability of Polyethylene Oxide in a Hydrophilic Matrix TabletThe effect of various fillers on the oxidative stability of polyethylene oxide (PEO) in a matrix tablet was studied. Tablet hardness, dissolution profiles, and polymer viscosity were studied over 3 months at accelerated aging conditions. Results indicate PEO stability can be affected by the type of filler used in the formulation.