• Core Excipients

  • Functional Excipients for the Formulation of Solid Oral Dosage Forms

  • Coatings

  • Fully Formulated Conventional and Modified Release Film Coating Systems
  • Formulation Tools

  • Useful Tools for the Pharmaceutical Formulator

  • Education

  • Technical formulation and development seminars and forums
  • Evaluate

  • Competitor, Consumer Color Preference, Regulatory, Tablet Library of Shapes, and Trademarks

  • Develop

  • Unique Tablet Designs and Branding Solutions

  • Visualize

  • Concept to Prototypes using State-of-the-Art 3D Images and Models through our Tablet Design Centers

  • Brand Security

  • Understand Options and Learn of New Technologies to Protect your Brand
  • Technical

  • Global Technical Support, Technical Service Labs and Tablet Design Centers

  • Regulatory

  • Global Regulatory Support Services

  • Customer

  • Global Customer Support and Service Locations
  • Tools

  • Useful Tools to Assist Pharmaceutical Product Development

  • Literature

  • Extensive Collection of Articles, Product Literature, Application Data and Regulatory Documents

  • Education

  • Technical Formulation and Development Seminars and Forums
 
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METHOCEL™ Cellulose Ethers (Controlled Release)

 

METHOCEL™ Premium grades have long been used by the pharmaceutical industry. There are two basic premium types, methylcellulose (MC) and hypromellose, which meet the standards set by the USP, JP, and Ph. Eur. 

Both types of METHOCEL™ have the polymeric backbone of cellulose, a natural carbohydrate that is based on a repeating structure of anhydrous units.

Colorcon now has exclusive, global sales and distribution rights for the following Dow Wolff Cellulosics' products used in controlled release applications: METHOCEL™ Premium hydroxypropyl methylcellulose (HPMC).

METHOCEL™ Cellulose Ethers are the first choice for the formulation of hydrophilic matrix systems, providing a robust mechanism for the slow release of drugs from oral solid dosage forms. With a choice of viscosity grades, METHOCEL™ provides a simple solution to meet a range of drug solubility needs. Tablets are easily manufactured with existing, conventional equipment and processing methods.

 Matrix Tablet Formulations
 

Application Benefits Typically Used METHOCEL Cellulose Ethers
Low Solubility Drugs Fast polymer hydration to form gel layer; non-ionic E50LV, K100LV, K100LV CR
Med to High Solubility Drugs Fast polymer hydration to form gel layer; non-ionic K4M, K15M, K100M, E4M, E10M, K4MCR, K15MCR, K100MCR, E4MCR, E10MCR

Product overview for the METHOCEL™ line of premium ethylcellulose polymers

 

 

 

 METHOCEL™ is a Trademark of Dow Wolff Cellulosics