METHOCEL™ Premium grades have long been used by the pharmaceutical industry. There are two basic premium types, methylcellulose (MC) and hypromellose, which meet the standards set by the USP, JP, and Ph. Eur.
Both types of METHOCEL™ have the polymeric backbone of cellulose, a natural carbohydrate that is based on a repeating structure of anhydrous units.
Colorcon now has exclusive, global sales and distribution rights for the following Dow Wolff Cellulosics' products used in controlled release applications: METHOCEL™ Premium hydroxypropyl methylcellulose (HPMC).
METHOCEL™ Cellulose Ethers are the first choice for the formulation of hydrophilic matrix systems, providing a robust mechanism for the slow release of drugs from oral solid dosage forms. With a choice of viscosity grades, METHOCEL™ provides a simple solution to meet a range of drug solubility needs. Tablets are easily manufactured with existing, conventional equipment and processing methods.
Matrix Tablet Formulations
| Application |
Benefits |
Typically Used METHOCEL Cellulose Ethers |
| Low Solubility Drugs |
Fast polymer hydration to form gel layer; non-ionic |
E50LV, K100LV, K100LV CR |
| Med to High Solubility Drugs |
Fast polymer hydration to form gel layer; non-ionic |
K4M, K15M, K100M, E4M, E10M, K4MCR, K15MCR, K100MCR, E4MCR, E10MCR |
Product overview for the METHOCEL™ line of premium methylcellulose polymers
METHOCEL™ is a Trademark of The Dow Chemical Company
