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Application of Surelease® in Preparation of Theophylline Extended Release Inert Matrix Tablets by Spray GranulationSurelease Application Data document
Investigation of Aqueous Ethylcellulose Dispersion in Extended Release Metformin Inert Matrices ADS adapted from 2009 CRS poster, Investigation of Aqueous Ethylcellulose Dispersion in Extended Release Metformin Inert Matrices
Stability of a Sparingly Soluble BCS Class I API Ethylcellulose Coated MultiparticulateThis ADS was adapted from the CRS 2010 poster investigating the long term stability, curing effects and release kinetics of a sparingly soluble BCS Class I API, layered on nonpareil beads and coated with aqueous Ethylcellulose dispersion.
The Influence of Hydrophilic Pore-Formers on Metoprolol Succinate Release from Mini-tabs Coated with Aqueous Ethylcellulose DispersionThis ADS was adapted from the CRS 2010 poster to investigate the influence of incorporating different levels of pore-former into aqueous EC system (Surelease) on the release of a freely water-soluble drug metoprolol succinate, from coated mini-tabs.
Surelease® E-7-19020 Product InformationFeatures and benefits of the Surelease E-7-19020, aqueous ethylcellulose coating system.
Surelease® E-7-19030 Product InformationFeatures and benefits of the Surelease E-7-19030, aqueous ethylcellulose coating system.
Surelease® E-7-19040 Product InformationFeatures and benefits of the Surelease E-7-19040, aqueous ethylcellulose coating system.
Surelease® E-7-19050 Product InformationFeatures and benefits of the Surelease E-7-19050, aqueous ethylcellulose coating system.
Surelease® Preparation and Use SheetOutline of the recommended dispersion mixing procedures, coating levels, and cleaning guidelines for the Surelease platform of aqueous ethylcellulose dispersions.
Surelease® Sales BrochureIntroduction to the Surelease platform of aqueous ethylcellulose dispersions.
AAPS 2011 - Barrier Membrane Coating of Hydrophilic Matrices of Sparingly Soluble Drug, Acetaminophen: A Strategy to Reduce Possible Food EffectTo investigate the application of a barrier membrane (BM) coating on APAP matrices, consisting of an aqueous ethylcellulose dispersion (Surelease® E-7-19010) and a pore former (Opadry® film coating) as a strategy to reduce drug release variability and possible food effect when dealing with hydrophilic matrices of a sparingly soluble model drug.
Application of Ethylcellulose in Preparation of Extended Release Theophylline Inert Matrix Tablets by Wet GranulationThe outcome of this study illustrates that an aqueous ethylcellulose dispersion (Surelease™) was successfully utilized to formulate and manufacture extended release theophyllin inert matrices. The influence of varying polymer concentration, filler choice and compression force on drug release profiles were studied as well.
Application of an Aqueous Ethylcellulose Dispersion in Multiple-Unit Pellet Systems.The objective of this poster reprint was to investigate drug release from compressed multiple-unit pellet systems, coated with an aqueous ethylcellulose dispersion (Surelease® E-7-19040).
CRS 2011 - Barrier Membrane Coating of Hydrophilic Matrices: A Strategy to Reduce Drug Release Variability and Possible Food EffectThe objective of the present study was to investigate the application of BM coating consisting of an aqueous ethylcellulose dispersion (Surelease® E-7-19010) and a pore former (Opadry®) as a strategy to reduce drug release variability from hydrophilic matrices as a function of hydrodynamics. The effect of coating weight gain and level of pore-former in the BM coating were also evaluated.
CRS 2011 - Barrier Membrane Coating of Hydrophilic Matrices: Influence of Tablet Shape and Geometry on Drug ReleaseThe shape and geometry of the matrix tablet is one of the critical parameters in determining the release rate from hydrophilic matrices.Barrier membrane coating of different shaped hydrophilic matrix tablets offers an opportunity for drug release modulation and tailoring the drug release profile in addition to advantages such as rebranding of existing products, and creating distinctive formulations.
CRS 2011 - The Influence of Aqueous Ethylcellulose Coating on the Performance of Hydrophilic Polyethylene Oxide Mini-Matrices Containing a Freely Water Soluble DrugRelease of freely water soluble metoprolol succinate from uncoated and sealcoated mini-matrices occurred within 3 hours. An application of Surelease® barrier membrane to mini-tabs resulted in extending drug dissolution up to 24 hours. As the weight gain of ethylcellulose coating increased, the release profile shifted towards zero order.
Comparative Study of Theoretical Versus Actual Weight Gain for a Surelease® Barrier Membrane on Coated PelletsThis poster reprint outlines an analytical method to determine the quantity of ethylcellulose applied during coating, on multiparticulates.
Effect of Hypromellose as a Pore-Former in Aqueous Ethylcellulose Dispersion: Characterization of Dispersion PropertiesThis poster reprint investigates the effect of HPMC as a pore-former on: stability of aqueous EC dispersion (Surelease®); quality of the free films prepared from these mixtures, and interactions between the HPMC and EC dispersion.
Evaluation of Alternative Plasticizers for Surelease®, an Aqueous Ethylcellulose Dispersion for Modified Release Film-CoatingThis poster reprint examines the effects of various plasticizers on the thermal and physical properties of ethylcellulose.
Hypromellose as a Pore Former in Aqueous Ethylcellulose Dispersion: Stability and Film PropertiesThis poster reprint investigates the effect of HPMC as a pore-former on: stability of aqueous EC dispersion (Surelease®); quality of the free films prepared from these mixtures, and interactions between the HPMC and EC dispersion.
Identification and Influence of Critical Coating Process Parameters on Drug Release from a Fully Formulated Aqueous Ethylcellulose DispersionThe objective of this poster reprint was to identify and study the influence of critical film coating process parameters for Surelease® aqueous ethylcellulose dispersion, on drug release behavior and the output or response variables of that process.
Investigation of the Relationship between Formulation Variables and Drug Release in Aqueous Ethylcellulose CoatingThis poster reprint summarizes the effect of pore former on the drug release of various actives from drug layered beads coated with Surelease®, aqueous ethylcellulose dispersion.
Predictability of Drug Release from Multiparticulate Systems Coated with an Aqueous Ethylcellulose DispersionThis poster reprint examines drug release from drug layered beads varying in substrate size, and Surelease® coating level.
The Effect of Hypromellose as a Pore-Former on Drug Release from Aqueous Ethylcellulose Film-Coated Dipyridamole-Loaded Non-Pareil BeadsThis poster reprint investigates the influence of pore-formers on the release of a poorly water-soluble drug, dipyridamole, from non-pareil beads coated with an aqueous ethylcellulose dispersion (Surelease® NG E-7-19050).
The Influence of Hydrophilic Pore Formers on Dipyridamole Release from Aqueous Ethylcellulose Film-Coated PelletsThis poster reprint studies the effect of incorporating water-soluble polyvinyl alcohol (PVA) and polyethylene glycol (PEG) as a pore former into Surelease® films, and how they influence dipryridamole release from the pellets.
The Influence of Plasticizer Type on the Film Properties of a Fully-Formulated Aqueous Ethylcellulose DispersionThis poster reprint examines the impact of choice of plasticizer on the dispersion behavior and film properties of a fully formulated aqueous ethylcellulose dispersion.
The Influence of Post Coating Thermal Treatment on Film Properties and Drug Release from Ethylcellulose Barrier Membrane Coating SystemsThe results of this study demonstrate that post coating treatment can affect both physico-mechanical properties of EC films and drug release from EC-coated multi-particulates.
