When developing a solid oral dosage form, factors such as appearance, taste, and aroma are important considerations. These properties can influence consumer preference and compliance for the dosage regimen, mainly in the case of high dose, poorly tasting drugs.
Water soluble film coatings can improve the appearance of a tablet, but taste masking has presented technical challenges. Typically, high levels of non water soluble coatings have been used, but this can add significant costs. In addition drug dissolution rates or bioavailability can be negatively affected.
Colorcon® offers several solutions to help with taste masking of drugs, along with technical expertise to assist with your challenging formulation.