• Core Excipients

  • Functional Excipients for the Formulation of Solid Oral Dosage Forms

  • Coatings

  • Fully Formulated Conventional and Modified Release Film Coating Systems
  • Formulation Tools

  • Useful Tools for the Pharmaceutical Formulator

  • Education

  • Technical formulation and development seminars and forums
  • Evaluate

  • Competitor, Consumer Color Preference, Regulatory, Tablet Library of Shapes, and Trademarks

  • Develop

  • Unique Tablet Designs and Branding Solutions

  • Visualize

  • Concept to Prototypes using State-of-the-Art 3D Images and Models through our Tablet Design Centers

  • Brand Security

  • Understand Options and Learn of New Technologies to Protect your Brand
  • Technical

  • Global Technical Support, Technical Service Labs and Tablet Design Centers

  • Regulatory

  • Global Regulatory Support Services

  • Customer

  • Global Customer Support and Service Locations
  • Tools

  • Useful Tools to Assist Pharmaceutical Product Development

  • Literature

  • Extensive Collection of Articles, Product Literature, Application Data and Regulatory Documents

  • Education

  • Technical Formulation and Development Seminars and Forums
 

Zero Order Release

The ability to deliver a drug at a rate which is independent of time and the concentration of drug within a pharmaceutical dosage form is desirable. Zero order mechanism ensures that a steady amount of drug is released over time, minimizing potential peak/trough fluctuations and side effects, while maximizing the amount of time the drug concentrations remain within the therapeutic window (efficacy). This is particularly important for 24 hour delivery of drugs with a narrow therapeutic index. Osmotic tablet formulations, coated tablet matrices, and the use of polymer combinations in hydrophilic matrices can be utilized to provide zero order drug release profiles.