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Enteric Release

Enteric coated dosage forms for delayed drug release profiles are a popular choice for the delivery of drugs where either protection from the harsh, acidic, environment of the stomach is required (proton pump inhibitors), or there is a need to reduce irritation of the gastric lining of the stomach commonly associated with certain types of medications (non-steroidal anti-inflammatories e.g. aspirin). In either case, enteric/delayed release coatings are intended to prevent release of the drug until the dosage form has passed through the stomach, followed by rapid release of the drug in the proximal small intestine. Such a release profile can be achieved through coating of multi-particulates or tablets with pH-dependent polymeric coating systems.

 
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