• Core Excipients

  • Functional Excipients for the Formulation of Solid Oral Dosage Forms

  • Coatings

  • Fully Formulated Conventional and Modified Release Film Coating Systems
  • Formulation Tools

  • Useful Tools for the Pharmaceutical Formulator

  • Education

  • Technical formulation and development seminars and forums
  • Evaluate

  • Competitor, Consumer Color Preference, Regulatory, Tablet Library of Shapes, and Trademarks

  • Develop

  • Unique Tablet Designs and Branding Solutions

  • Visualize

  • Concept to Prototypes using State-of-the-Art 3D Images and Models through our Tablet Design Centers

  • Brand Security

  • Understand Options and Learn of New Technologies to Protect your Brand
  • Technical

  • Global Technical Support, Technical Service Labs and Tablet Design Centers

  • Regulatory

  • Global Regulatory Support Services

  • Customer

  • Global Customer Support and Service Locations
  • Tools

  • Useful Tools to Assist Pharmaceutical Product Development

  • Literature

  • Extensive Collection of Articles, Product Literature, Application Data and Regulatory Documents

  • Education

  • Technical Formulation and Development Seminars and Forums
 

Ascending Release

Ascending drug release profiles are characterized by an initial slow rate of drug release, followed by an increase in the rate for the latter stages of drug release. The primary drivers for the need to deliver a drug in such a manner exists where there is a localized target for drug delivery, for chronotherapeutic delivery where faster drug release at night-time results in high concentration of drug for early morning therapeutic treatment e.g., anti-inflammatory analgesia for arthritis, asthma and early morning cardio-protection. Or this may just be a strategy to compensate for low absorption of some drug in the distal intestine.